Neurology

Adding Tumor Lysate-Loaded Autologous Dendritic Cell Vaccination to Standard of Care Associated with Clinically Improved Overall Survival in Patients With Newly Diagnosed and Recurrent Glioblastoma |  Medicine in 2 Minutes

Adding Tumor Lysate-Loaded Autologous Dendritic Cell Vaccination to Standard of Care Associated with Clinically Improved Overall Survival in Patients With Newly Diagnosed and Recurrent Glioblastoma | Medicine in 2 Minutes

1. In this phase 3 non-randomized controlled trial, among 331 patients, patients with newly diagnosed glioblastoma (nGBM) receiving dendritic cell vaccination (DCVax-L) had a median overall survival of 19.3 months versus 16.5 months in outpatient control patients treated with standard of care. 2. Patients with recurrent glioblastoma (rGBM) had a median overall survival of 13.2 …

Adding Tumor Lysate-Loaded Autologous Dendritic Cell Vaccination to Standard of Care Associated with Clinically Improved Overall Survival in Patients With Newly Diagnosed and Recurrent Glioblastoma | Medicine in 2 Minutes Read More »

ENT-01 reduces constipation rates in patients with Parkinson's disease |  Medicine in 2 Minutes

ENT-01 reduces constipation rates in patients with Parkinson’s disease | Medicine in 2 Minutes

1. Compared to placebo, ENT-01 increased weekly complete spontaneous stool rates in patients with Parkinson’s disease (PD). 2. No serious adverse events occurred with the use of ENT-01 and the most frequently reported adverse effect was nausea. Level of evidence assessment: 1 (Excellent) Summary of the study: Non-motor symptoms of PD can significantly impair a …

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Guidelines for MS clinicians: talking about brain atrophy

Guidelines for MS clinicians: talking about brain atrophy

A team of researchers from the Jacobs School of Medicine and Biomedical Sciences, working alongside people with MS and their advocates, have developed guidelines for clinicians on how to discuss brain atrophy with patients. Published November 14, 2022 Ellen Goldbaum story A team of researchers from the Jacobs School of Medicine and Biomedical Sciences has …

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Dr. Daniel B. Drachman, Neuromuscular Disease Expert and Founder of Johns Hopkins Department of Neurology, Dies

Dr. Daniel B. Drachman, Neuromuscular Disease Expert and Founder of Johns Hopkins Department of Neurology, Dies

Dr. Daniel B. Drachman, one of the world’s leading authorities on neuromuscular diseases and founder of the Department of Neurology at the Johns Hopkins School of Medicine, who also helped world-renowned pianist Leon Fleisher regain the use of his right hand and to return to the concert stage, died of a heart attack and infection …

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