Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease - BMC Medicine

Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease – BMC Medicine

The present study shows that children with untreated CD have lower expression of genes involved in IGN in duodenal biopsies compared to children with normal intestinal mucosa. Decreased expression correlates with higher Marsh score and, to a lesser extent, tTG antibody levels. These results suggest that CD patients may have impaired IGN function, either due …

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