gastroenterology

Harmful gut bacteria co-opt genetic susceptibility to trigger Crohn's disease

Harmful gut bacteria co-opt genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to trigger the inflammation that leads to Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian researchers. These findings could one day help doctors better select targeted treatments for patients with this immune disorder. This particular host gene, …

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ENT-01 reduces constipation rates in patients with Parkinson's disease |  Medicine in 2 Minutes

ENT-01 reduces constipation rates in patients with Parkinson’s disease | Medicine in 2 Minutes

1. Compared to placebo, ENT-01 increased weekly complete spontaneous stool rates in patients with Parkinson’s disease (PD). 2. No serious adverse events occurred with the use of ENT-01 and the most frequently reported adverse effect was nausea. Level of evidence assessment: 1 (Excellent) Summary of the study: Non-motor symptoms of PD can significantly impair a …

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