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Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease - BMC Medicine

Retinal age difference as a predictive biomarker of stroke risk – BMC Medicine

Study population The UK Biobank is a large-scale prospective population-based cohort study of 502,656 UK residents aged 40-69 who were registered with the National Health Service (NHS). Overall study protocols and data are available elsewhere [24]. Briefly, baseline assessments were carried out between 2006 and 2010 at 22 assessment centers across the UK. Participants completed …

Retinal age difference as a predictive biomarker of stroke risk – BMC Medicine Read More »

Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease - BMC Medicine

Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease – BMC Medicine

The present study shows that children with untreated CD have lower expression of genes involved in IGN in duodenal biopsies compared to children with normal intestinal mucosa. Decreased expression correlates with higher Marsh score and, to a lesser extent, tTG antibody levels. These results suggest that CD patients may have impaired IGN function, either due …

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